Muscle biopsies from sedentary COPD patients vs. Muscle biopsies from healthy sedentary controls

Microarray analysis of vastus lateralis biopsies from chronic obstructive pulmonary disease (COPD) patients compared to similar biopsy samples from aged-matched healthy individuals.

Skeletal muscle biopsies were collected from 9 stable COPD patients with a normal fat-free mass index (FFMI, 21Kg/m2) (COPDN), 6 COPD patients with a low FFMI (16Kg/m2) (COPL), and 12 healthy sedentary subjects (FFMI 21Kg/m2).