Browser Not Supported.
IE users: please get the latest browser version at Microsoft Internet Explorer Home Page
if yot already have the latest browser version please verify that your browser settings is not in compatibility mode
The substantia nigra (SN) is positioned in the basal plate domain of the mesencephalon (midbrain). It is divided into superficial (pars reticularis, or SNR) and deep (pars compacta, or SNC) portions. The SNC is populated by dopaminergic neurons (also called the A9 dopaminergic neuron group) that innervate the dorsal striatum (caudet and putamen), participating in movement control. Parkinson's disease is characterized by the death of dopaminergic neurons in this compartment.