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The temporomandibular joint (TMJ) is a complex skeletal structure that mediates, and is essential for normal functioning of the jaw. It consists of condylar cartilage, an articular disc, and upper and lower joint cavities (articular fossa). The TMJ can be morphologically identified at E18.5
In mammalian embryos, the first overt step in mandibular condyle development is the appearance of ecto-mesenchymal cell condensation at the supralateral distal site of the jaw anlagen.