Browser Not Supported.

IE users: please get the latest browser version at Microsoft Internet Explorer Home Page

if yot already have the latest browser version please verify that your browser settings is not in compatibility mode

Browser: unknown
Version: 0

EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
Content

Welcome to
LifeMap Discovery

Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine

All Anatomical Compartments > Compartment Card
Heart >

Myocardium


Hrt.Mcrdm
Heart muscle cells, typically arising from progenitor cells of both the first and second heart fields, undergo spatially and temporally controlled maturational steps, which yield their fully differentiated adult phenotypes. The myocardium is composed of myocardial cells, which are striated muscle cells featuring myofibrils. The myofibrils, built of numerous myofilaments,, are visible threads that run parallel to the long axis of the cells and provide contractive capacities to these cells. Early myocardial development is characterized by subdivision of the myocardial wall into the outer, highly mitotic compact zone and an inner trabecular zone, which has much less proliferative activity. The compact zone (recognizable at E11.5) is essential for myocardial growth, while the trabeculated myocardium functions in myocardial perfusion (E9.5-13.5). During cardiac looping, cardiac jelly, or the extracellular matrix, is largely secreted between the endocardium and myocardium. The cardiac jelly region is populated by cushion cells and is important for propagation, integration, regionalization and/or stabilization of endocardial signals.
Heart Muscle Cells
Myocardium
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent