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EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
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All Anatomical Compartments > Compartment Card
Heart >

Outflow Tract Cushion


Hrt.OTC
The outflow tract cushion tissue arises from the cardiac neural crest, from the endocardium and from pharynx-derived mesenchyme, and plays a critical role in proper separation of the aorta from the pulmonary artery. This type of cushion tissue contains both truncal and distal cushions. The truncal cushion tissues are further remodeled to form the aortic and pulmonary semilunar valves.

Defective separation of the aorta from the pulmonary artery results in persistent truncus arteriosus, common trunk and overriding aorta.
Outflow Tract
Outflow Tract Cushion
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent