Mesangial cells are fibroblast-like cells interposed between the glomerular capillaries.
On a functional level, mesangial cells resemble pericytes in the vascular support they provide. The cells share the same origin as vascular smooth muscle cells and pericytes. All three cell types line the extraglomerular vasculature.
Mesangial precursors appear to be derived from the metanephric mesenchyme and reside in the stroma.
Mesangial cells are involved in providing structural support to the newly formed vessels by synthesizing the surrounding extracellular matrix (ECM).
Multiple AncestorsSingle AncestorNo DescendantsDevelops fromPart of Parent