Angioblasts migrate into the kidney developing nephron, make cell-cell contact and differentiate into kidney endothelial cells and form capillaries adjacent to podocytes, consequentially triggering glomerular development.
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Angioblasts invading the capillary cleft of developing nephrons at the S-shaped stage first undergo homotypic aggregation into precapillary cords, without a recognizable lumen. Assembly of renal microvascular endothelial cells into precapillary cords occurs through homotypic interactions between cells and regulated by Eph-like kinase (ELK) receptors.
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Multiple AncestorsSingle AncestorNo DescendantsDevelops fromPart of Parent