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EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM

Lateral Plate Mesoderm > Aorta-Gonad-Mesonephros
LtPM.AGM

The aorta-gonad-mesonephros (AGM) region extends from the umbilical cord to the anterior limb bud and contains the dorsal aorta. At around E11 (mouse), or day 22.5 of gestation (human), multipotent hematopoietic cells from the dorsal aorta colonize the fetal liver (liver bud).


Notch1 signaling is important for hematopoiesis within the AGM but not within the yolk sac.

Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent
Version 1.1 Build 20