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Welcome to
LifeMap Discovery

Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine

All in Vivo Cells > Cell Card

Mural cells are progenitors of smooth muscle cells (SMCs) and pericytes. As the endothelial tubes invade organ primordia, they become surrounded by locally-derived mesenchymal cells (precursors of mural cells). Hence, the primordium itself contributes the mural cell layer(s) to the developing vessels, which may result in tissue-specific functional and regulatory properties of pericytes, and SMCs. This is in contrast to endothelial cells, which are thought to be of uniform origin.

Varying levels of TGF may activate Alk1 and Alk5 in a differential manner
Perivascular cells
Pericytes, Smooth Muscle
Mural Cells
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent