EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
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Zone Of Polarizing Activity Cells (LB)


Lmb.LB.ZPACs
Zone of polarizing activity cells form a subset of cells in the posterior mesenchyme of the limb bud. They are the main source of SHH signaling in the developing limb.

Directs anterio-posterior patterning of the limb (thumb to digit 5).
Prenatal
ZPA
Mesoderm
Zone Of Polarizing Activity Cells
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent
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