EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
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Alveolar Epithelial Type 2 Cells (Alv)


Lng.Alv.AEC2

Alveolar Epithelial Type 2 Cells (AEC-2) are large, cuboidal cells whose main function is to produce surfactant.  These cells can self-renew and transdifferentiate into AEC-1.  AEC-2 can be distinguished at the ultrastructural level by the presence of lamellar bodies and microvilli. 


Multipotent cell. SP-C expression is considered a unique marker of mature AEC-2.

E16.5 - Postnatal
Pneumocytes
Lung
Epithelial Cells
Alveolar Epithelial Type 2 Cells
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent
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