Cardiac Progenitor Cells (Msd)

The cardiac progenitor cells are thought to originate from epiblast cells which reside in the lateral sides of the primitive streak at the early gastrula stage. These cells then ingress into the cranial portion of the primitive streak as part of the mesoderm, and start their bilateral and cranial migration along a semicircular trajectory, with little or no cellular mixing. These cardiogenic progenitor cells later give rise to both the myocardium and the endocardium, in addition to two non-cardiac populations (dorsal mesocardium and the parietal pericardium cells).