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LifeMap Discovery

Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine

All in Vivo Cells > Cell Card
Dorsal Pancreatic Bud

Alpha Progenitor Cells (DPB)


Alpha progenitor cells precede the mature alpha cell phenotype. These cells display alpha cell lineage genes but do not produce nor secrete the glucagon hormone. During the secondary transition alpha progenitor cell proliferation occurs along with continous differentiation.

In the pancreas the differentiation of endocrine cells is non-synchronous and lasts from the secondary transition period (which is the major time of endocrine cell differentiation) to the postnatal period.

E9.5 - Postnatal
Alpha Progenitor Cells
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent