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EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
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All in Vivo Cells > Cell Card
Pancreas
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Dorsal Pancreatic Bud
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Bipotent Endocrine/Duct Progenitor Cells (DPB)


Pnc.DPB.BEDPCs
Bipotent endocrine/duct progenitor cells are a subset of pancreatic progenitor cells with the potential to differentiate to either endocrine cells or duct cells. These cells reside in a centrally located domain of the pancreatic epithelium. The majority of endocrine cells differentiate from these bipotent progenitor cells during the secondary transition. The fate-potential of these cells correlates with the phenotype of cells known as "trunk" cells (located in the trunk portion of the developing duct-acinar morphology).

An alternative lineage hypothesis exists, however the presented developmental mapping, that involves a bipotent endocrine/duct progenitor cell, is based on the excellent reviews of Pan et al. (2011) and Pierreux et al.(2010).
Prenatal - Postnatal
Multipotent trunk cells
Bipotent Endocrine/Duct Progenitor Cells
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent