Foregut endoderm area containing Pdx1 positive pancreatic progenitors. Forms the dorsal pancreatic bud. Commitment to a pancreatic fate occurs as early as E8–E8.5 in mice. Permissive signals released from adjacent mesodermal structures, and the notochord are important for induction of the pancreatic program.
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Multiple AncestorsSingle AncestorNo DescendantsDevelops fromPart of Parent