Co-infusion of umbilical cord blood and haploidentical CD34+ cells for hematological diseases

The aim of this study is to evaluate the safety and efficacy of co-administration of patients with severe aplastic anemia (SAA) or myelopdysplastic syndrome (MDS) with a relatively low number of haploidentical T-cell depleted peripheral blood and CD34+ enriched stem cells from a family member, together with umbilical cord blood (UCB) stem cells from an unrelated donor.