Ovation® is a matrix of placental mesenchyme and of mesodermal origin. It includes extracellular matrix, mesenchymal stem cells (MSCs) and growth factors and is used to support bone repair, mainly spinal fusion.
Ovation® provides a 3-dimensional architecture that has all of the necessary cellular and molecular components for wound healing. More specifically, Ovation® provides the three essential components of the periosteum—collagen matrix, viable endogenous MSCs and key growth factors, such as bone morphogenic proteins and vascular endothelial growth factor — to enable tissue regeneration.
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There is limited published data on the composition of the matrix.
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