Embryonic stem cell-derived neural stem cells for ischemic stroke

This study aims to test the potential of embryonic stem cell-derived neural stem cells in treating ischemic stroke. Neural stem cells were differentiated from human embryonic stem cells, and were then transplanted into the brains of a stroke animal model. The transplanted cells migrated into the ischemic region, and differentiated into gamma-aminobutyric acid (GABA)-secreting neurons. The transplanted cells did not form any tumors or overgrowth. Moreover, they improved the sensorimotor function of the stroke-disabled forelimb.