NU215-01, mesenchymal stem cells for treatment of systemic lupus erythematosus

The aim of this study was to determine the safety and efficacy of treatment of systemic lupus erythematosus (SLE) with allogeneic umbilical cord-derived mesenchymal stem cells (UC-MSCs). The findings indicate that UC-MSC transplantation results in amelioration of disease activity, serologic changes, and stabilization of proinflammatory cytokines.