Stem cell-derived dopaminergic neurons to treat Parkinson's disease

This study aims to test the therapeutic potential of embryonic stem cell-derived dopaminergic neurons for the treatment of Parkinson's disease. The stem cell-derived dopaminergic neurons were injected into the brains of Parkinson's disease monkey models. Three months after the injection, 10% of the grafted cells exhibit a dopaminergic neurons phenotype, and extended long, synaptophysin-positive processes, as visualized by immunohistochemical analysis.