Ornithine Transcarbamylase Deficiency, Hyperammonemia Due to

- Cell Therapy Approaches

Ornithine transcarbamylase deficiency (OTCD) is a metabolic urea cycle disorder caused by impaired enzyme ornithine transcarbamylase function, resulting in ammonia accumulation in the blood, causing hyperammonemia.

Cell Therapy Approaches

Cell therapy utilizing hepatocytes or liver-derived stem/progenitor cell transplantation has the potential to relieve disease symptoms. Liver-derived stem/progenitor cells will differentiate into mature, healthy liver cells that can produce ornithine transcarbamylase enzyme and restore the normal urea cycle, thereby relieving disease symptoms.

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Ornithine Transcarbamylase Deficiency, Hyperammonemia Due to

- Cell Therapy Approaches

Cell Therapy Approaches

Cell Therapies for the treatment of

Modeling of

Affected or Therapy-targeted Cells/Compartments for

Literature related to

Welcome to LifeMap Discovery

Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine

Ornithine Transcarbamylase Deficiency, Hyperammonemia Due to - Cell Therapy Approaches

Cell Therapy Approaches

Cell Therapies for the treatment of

Modeling of

Affected or Therapy-targeted Cells/Compartments for

Literature related to

Welcome to
LifeMap Discovery

Ornithine Transcarbamylase Deficiency, Hyperammonemia Due to

- Cell Therapy Approaches