Pelizaeus-Merzbacher Disease

- Cell Therapy Approaches

Pelizaeus–Merzbacher disease (PMD) is a congenital hypomyelination disorder that belongs to a group of genetic disorders called leukodystrophies that affect myelin sheath growth. PMD is caused by a mutation in the myelin protein proteolipid protein 1 (PLP1).

Cell Therapy Approaches

The objective of PMD cell therapy is to achieve myelin sheath repair. Glial progenitor cells (GPCs), which can give rise to new myelinogenic oligodendrocytes, are potential therapeutic cells for the restoration of myelin to the hypomyelinated or dysmyelinated central nervous system axons.

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Pelizaeus-Merzbacher Disease

- Cell Therapy Approaches

Cell Therapy Approaches

Cell Therapies for the treatment of

Modeling of

Affected or Therapy-targeted Cells/Compartments for

Literature related to

Welcome to LifeMap Discovery

Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine

Pelizaeus-Merzbacher Disease - Cell Therapy Approaches

Cell Therapy Approaches

Cell Therapies for the treatment of

Modeling of

Affected or Therapy-targeted Cells/Compartments for

Literature related to

Welcome to
LifeMap Discovery

Pelizaeus-Merzbacher Disease

- Cell Therapy Approaches