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EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
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Welcome to
LifeMap Discovery

Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine

Highly efficient and large-scale generation of functional dopaminergic neurons from stem cells

A protocol for efficient, large-scale generation of functional dopaminergic (DA) neurons from human embryonic stem cells (hESCs), via the intermediate generation of homogeneous spherical neural masses (SNMs). These SNMs can be passaged many times without losing their differentiation capability and can be coaxed into DA neurons at high efficiency (86% of the total initiated neurons are tyrosine hydroxylase-positive neurons).
62-79 days
See additional Protocols for: Dopaminergic Neurons , Neural Ectoderm
Highly efficient and large-scale generation of functional dopaminergic  neurons from stem cells