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EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
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Welcome to
LifeMap Discovery

Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine

Generation of syncytiotrophoblast cells from human embryonic stem cells

Human embryonic stem cells are induced to differentiate into syncytiotrophoblast cells by exposure to BMP4, which is coupled with inhibition of both activin/nodal and FGF signaling. The differentiated cells secrete βhCG hormone, are multinucleated and express syncytiotrophoblast-specific markers.
5-7 days
See additional Protocols for: Placenta
Generation of syncytiotrophoblast cells from human embryonic stem cells