EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
Content
All in Vivo Cells > Cell Card
Liver
>
Liver Lobule
>

Perivenous Hepatocytes (LvL)


Lvr.LvL.PvHpTs
Perivenous hepatocytes are exposed to lower oxygen tension, and lower nutrient and hormone levels, than periportal hepatocytes.

In the periportal regions, b-catenin activity, which is important for zonal gene expression in perivenous hepatocytes, is antagonized by adenomatous polyposis coli (APC). In mice, liver zonation is evident only in the first week following birth
Prenatal - Postnatal
Pericentral hepatocytes
Perivenous Hepatocytes
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent