RevaFlex™, formerly known as DeNovo ET® engineered tissue graft, is an engineered cartilage implant intended to repair cartilage defects in the knee. It is comprised of scaffold-free living articular cartilage, displaying biochemical properties similar to those of articular cartilage found in young, healthy joints. The tissues are recovered from juvenile donor joints and are intended for the repair of articular cartilage in a wide range of anatomic focal cartilage defects, including:
· Knee (i.e., condyle, trochlea, patella, tibial plateau)
· Foot and ankle (i.e.,talus,Metatarso-phalangeal joint)
· Shoulder (i.e., humeral head, glenoid)
· Hip (i.e., acetabulum, femoral head)
Treated patients experience significant improvement in pain and function.