Cardiosphere-derived autologous stem cells for reverse ventricular dysfunction

Cardiosphere-derived stem cells (CDCs) are cells grown from small biopsy samples taken from the heart. This study aims to determine the safety of administration of CDCs to patients with decreased heart function and/or a large amount of damaged muscle after a heart attack. Giving a patient their own CDCs is an investigational procedure that has been approved by the FDA for this study. In addition to determining whether this treatment is safe, the study will also examine whether it can decrease the amount of heart muscle damage and/or improve heart function after a heart attack. The amount of heart muscle damage and the function of the heart directly affects prognosis and the development of heart failure and other complications after a heart attack.