Combination therapy of mononuclear cells with laser for coronary disease

This trial aims to study the combinatorial effect of autologous bone marrow mononuclear cell therapy in tandem with transmyocardial revascularization (a surgical procedure that uses a laser to create channels through the myocardium). The PHOENIX™ device is capable of distributing stem cells within the channels created by the laser, essentially simultaneously performing both procedures. The procedure was feasible, with no complications and resulted in clinical improvement of patients. A reduction in the angina class, the number of cardiovascular medications and cardiac-related hospital admissions were recorded.