BioSeed®-C is is comprised of autologous chondrocytes assembled in a bioresorbable, two-component, three dimensional, gel-polymer scaffold.
A ~250 mg healthy articular cartilage biopsy from a non-weight bearing region of the knee was collected. Chondrocytes were expanded in vitro, under GMP conditions, for 4.5 weeks and then rearranged three dimensionally in a fibrin and a polymer-based scaffold of polyglycolic/polylactic acid (polyglactin, vicryl) and polydioxanone.