Reprogrammed glycogen storage disease type 1a cells (University of Cambridge)

Induced pluripotent stem cells (iPSCs) were generated from fibroblasts derived from a 25-year-old male with glycogen storage disorder, caused by the absence of glucose-6-phosphate enzyme. The donated tissue was infected with a mix of moloney murine leukemia virus-derived vectors, each containing the coding sequences of one of the following human genes: OCT4, SOX2, c-MYC, or KLF4. Cells express pluripotency markers, demonstrate alkaline phosphatase activity, and form teratomas which contain cells from all the three germ layers.

Isolation & Growth Conditions

Cells were cultured on irradiated mouse feeder cells in human ES cell culture medium (KSR) supplemented with bFGF (4 ng/ml).

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Reprogrammed glycogen storage disease type 1a cells (University of Cambridge)

Reprogramming Information for

Reprogrammed glycogen storage disease type 1a cells

Gene Expression in

Reprogrammed glycogen storage disease type 1a cells

Matched In Vivo Cells / Anatomical Compartments for

Reprogrammed glycogen storage disease type 1a cells

Culturing Conditions Tested for

Reprogrammed glycogen storage disease type 1a cells

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Reprogrammed glycogen storage disease type 1a cells

Cell Therapies Related to

Reprogrammed glycogen storage disease type 1a cells

Literature related to

Reprogrammed glycogen storage disease type 1a cells

Welcome to LifeMap Discovery

Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine

Reprogrammed glycogen storage disease type 1a cells (University of Cambridge)

Reprogramming Information for Reprogrammed glycogen storage disease type 1a cells

Gene Expression in Reprogrammed glycogen storage disease type 1a cells

Matched In Vivo Cells / Anatomical Compartments for Reprogrammed glycogen storage disease type 1a cells

Culturing Conditions Tested for Reprogrammed glycogen storage disease type 1a cells

Protocols Related to Reprogrammed glycogen storage disease type 1a cells

Cell Therapies Related to Reprogrammed glycogen storage disease type 1a cells

Literature related to Reprogrammed glycogen storage disease type 1a cells

Welcome to
LifeMap Discovery

Reprogramming Information for

Reprogrammed glycogen storage disease type 1a cells

Gene Expression in

Reprogrammed glycogen storage disease type 1a cells

Matched In Vivo Cells / Anatomical Compartments for

Reprogrammed glycogen storage disease type 1a cells

Culturing Conditions Tested for

Reprogrammed glycogen storage disease type 1a cells

Protocols Related to

Reprogrammed glycogen storage disease type 1a cells

Cell Therapies Related to

Reprogrammed glycogen storage disease type 1a cells

Literature related to

Reprogrammed glycogen storage disease type 1a cells