Direct reprogramming of mouse fibroblasts into tripotent neural precursor cells
This protocol describes the direct reprogramming of fibroblasts into proliferative neural precursor-like cells by expression of the following genes: Brn2, Sox2 and Foxg1. These cells are tripotent neural precursor cells that can give rise to neurons, astrocytes and oligodendrocytes.
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Direct reprogramming of mouse fibroblasts into tripotent neural precursor cells