LifeMap Discovery™ is a state-of-the-art roadmap of embryonic development, stem cell biology and regenerative medicine.
The novel integration of hand-curated and reconstructed embryonic development with stem cell biology, molecular, cellular,
anatomical and disease-related information, provides an efficient and easy-to-use searchable, research tools. LifeMap Discovery™
brings together knowledge from the worlds of in vivo and in vitro research, as well as from in vitro to clinical translation
efforts, and can thus be utilized as a powerful tool for research and progress in stem cell biology, developmental biology,
disease mechanisms and therapeutic discovery.
Mar 24, 2013 - Public release of LifeMap Discovery™ version 1.1
The new release includes significant additions to our comprehensive in-vivo embryonic developmental paths, which describe differentiation
of cells from their early ancestors (primary progenitors) to specific cell fates. It also includes information on new progenitor and primary
cells and annotated cell differentiation protocols. Notably, it includes information for cells involved in diseases, such as Parkinson’s
disease and Age Related Macular Degeneration, both desired targets for cell therapy using dopaminergic neurons and retina cells, respectively.
In addition, the new version includes a large number of genes relevant to mapped developmental paths and stem cells, enabling researchers to
discover cellular and anatomical context of thousands of genes by using the powerful LifeMap Discovery™ gene search engine.
