Microarray analysis of brain tissue from frontotemporal dementia patients

Microarray gene expressin profiling of frontal cortex tissue obtained from frontotempotal dementia (FTD) patients. Postmortem frontal cortex tissue samples were isolated from patients with subtype of FTD: lobar degeneration with ubiquitin positive inclusions (FLD-U). FLD-U patients were divided into two groups: FLD-U patients with (n=6) and without (n=10) GRN gene mutations. Patients samples were compared with  age- and sex-matched control samples (n=8). This microarray experiment contains additional brain samples from the hippocampus and the cerebellum, which were excluded from LifeMap analysis.