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EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
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Welcome to
LifeMap Discovery

Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine

All in Vivo Cells > Cell Card
Brain
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Forebrain White Matter
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Oligodendrocyte Precursor Cells (FWM)


Brn.FWM.OPCs
Oligodendrocyte precursor cells (OPCs) are migratory cells which populate the developing cortex. These cells are derived from neuroepithelial cells within the ventricular zone of anterior entopeduncular and from medial, lateral and caudal ganglionic eminence domains within the ventral telencephalon. These cells migrate and maturate into myelinating oligodendrocytes that populate the forebrain white matter. At birth, oligodendrocytes are also derived from the cortex itself. Most of the early-born oligodendrocytes disappear after birth; thus, the majority of mature oligodendrocytes are cortical-derived cells.

In mice, these cells migrate at E16 and postnatally mature into myelinating oligodendrocytes.
E16 - Postnatal
Oligodendrocyte Progenitors (OLPs)
Oligodendrocyte Precursor Cells
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent