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LifeMap Discovery

Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine

All Anatomical Compartments > Compartment Card
Cartilage >

Intervertebral Disc

The intervertebral disc (IVD) is a cartilogenous structure that lays between the adjacent vertebrae and allows transferring loads and partial movement of the spine. Notochord gives rise to the central nucleus pulposus (NP) compartment of the IVD. NP is rich in aggrecan and hyaluronan. Sclerotome gives rise to the annulus fibrosus (AF) compartment of the IVD which surrounds the NP. The outer fraction of AF is rich in Collagen I, whether the inner is rich in Collagen II and proteoglycans. In adult, IVD is avascular.
Intervertebral Disc
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent