Foregut endoderm area containing Pdx1 positive pancreatic progenitors. Forms the dorsal pancreatic bud. Commitment to a pancreatic fate occurs as early as E8–E8.5 in mice. Permissive signals released from adjacent mesodermal structures, and the notochord are important for induction of the pancreatic program.
Multiple AncestorsSingle AncestorNo DescendantsDevelops fromPart of Parent