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EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
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All in Vivo Cells > Cell Card
Hair
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Hair Follicle
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Fetal Matrix Cells (HF)


Hair.HF.FMxCs
Fetal matrix cells are lineage-restricted precursors of the inner root sheath (IRS) and hair shaft (HS) layers, organized in proximo-distal columns adjacent to the dermal papilla (DP). Matrix cells undergo asymmetric cell division upon Noggin signaling from the DP, and produce daughter cells for the next layer. In turn, the daughter cells symmetrically divide and generate the layer of post-mitotic cells, located far from the DP, which can undergo terminal differentiation.

Germ-peg stage (stages 2-5). up to P14-18
Prenatal - Postnatal
Transiently Amplifying Cells
Fetal Matrix Cells
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent