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EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
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All in Vivo Cells > Unified Cell Card
Hair
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Inner Root Sheath
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Fetal Inner Root Sheath Cells (IRS)


Hair.IRS.FIRSCs
Inner root sheath cells make up the most inner epithelial layer enveloping the hair shaft. These cells for three layers: inner root sheath cuticle, Huxley's layer and Henle's layer.

Fetal inner root sheath cells are formed at bulbous peg stage (stages 6-8) of hair formation. The gene expression that appears in fetal inner root sheath cells reflects the collective expression of genes in all three types of cells: cuticle, Henle and Huxley cells.
Prenatal
Fetal Inner Root Sheath Cells
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent