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Welcome to
LifeMap Discovery

Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine

All in Vivo Cells > Cell Card
Neural Tube
Mesencephalic Floor Plate

Early Floor Plate Cells (MFP)

Neuronal stem cells located at the mesencephalon floor plate are first patterned to a ventral cell fate and away from a dorsal fate by a combination of SHH and FGF8 gradient. Some of these cell will differentiate into dopaminergic precursor cells, and the others will retain a general ventral neuronal characteristics and serve as organizer cells to the developing dopaminergic lineage. 
E7.5 - E10.5
Early Floor Plate Cells
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent