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EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
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All in Vivo Cells > Cell Card
Peripheral Nervous System
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Peripheral Nerve Domain
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Pro-myelinating Schwann Cells (PrND)


PNS.PrND.PMSCs
Promyelinating Schwann cells make up a transient population which arises from immature Schwann cells in the developing nerves, in response to specific axonal signals. These cells demonstrate reduced mitotic activity and form a 1:1 relationship with axons. They then form a basement membrane and begin to extend their plasma membrane around axons to yield a compact myelin structure that facilitates the propagation of axon potentials.
Prenatal - Postnatal
Pro-myelinating Schwann Cells
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent