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EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
Content

Welcome to
LifeMap Discovery

Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine

All in Vivo Cells > Cell Card
Peripheral Nervous System
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Peripheral Nerve Domain
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Schwann Precursor Cells (PrND)


PNS.PrND.SPCs
Schwann precursor cells (SPCs) are the stage between neural crest stem cells and Schwann cells. SPCs migrate with axons and provide essential trophic support to embryonic sensory and motor neurons. In addition, SPCs are essential for normal nerve fasciculation. A small fibroblast population found in the peripheral nerves is thought to develop from SPCs.

Most of the developmental data provided in the database for Schwann cells have been derived from research performed on Schwann cells located in or purified from a sciatic nerve, the largest and longest spinal nerve which begins in the lower back and runs through the buttock and down the lower limb.
E12 - E15
Schwann Precursor Cells
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent