Buerger Disease

- Cell Therapy Approaches

Thromboangiitis obliterans (TAO, Buerger's disease) involves progressive inflammation and thrombosis of arteries and veins of the extremities, characterized by pain in the affected areas, at rest and while walking. Cigarette smoking has been implicated as the primary etiology of the disease.

Cell Therapy Approaches

Cell therapy for necrosis in the legs of patients with TAO may improve symptoms through vascular regeneration and induction of neoangiogenesis. Studies indicate that autologous bone marrow stem cell therapy improves the clinical status and reduces amputation factors in the limbs with symptomatic TAO. Peripheral blood-derived mononuclear stem cells and adipose tissue-derived mononuclear stem cells have been shown to be effective in preventing disease progression, decrease major amputation rates, and improving quality of life.

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Buerger Disease

- Cell Therapy Approaches

Cell Therapy Approaches

Cell Therapies for the treatment of

Modeling of

Affected or Therapy-targeted Cells/Compartments for

Literature related to

Welcome to LifeMap Discovery

Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine

Buerger Disease - Cell Therapy Approaches

Cell Therapy Approaches

Cell Therapies for the treatment of

Modeling of

Affected or Therapy-targeted Cells/Compartments for

Literature related to

Welcome to
LifeMap Discovery

Buerger Disease

- Cell Therapy Approaches