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EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
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Generation of dopaminergic neurons from human pluripotent stem cells under defined conditions

This protocol describes a method to generate functional dopaminergic neurons via the formation of neural rosettes and isolation of neural stem progenitor cells. When the dopaminergic-like neurons were transplanted into the brains of 6-OHDA-induced Parkinson's disease animal models, cells survived and ameliorated the behavioral deficits of the animal models.
45 days
See additional Protocols for: Dopaminergic Neurons , Neural Ectoderm
Generation of  dopaminergic neurons from human pluripotent stem cells under defined conditions