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EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM
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Welcome to
LifeMap Discovery

Watch the introductory video to learn more about our database of embryonic development for stem cell research and regenerative medicine

Generation of dopaminergic neurons from human pluripotent stem cells under defined conditions

This protocol describes a method to generate functional dopaminergic neurons via the formation of neural rosettes and isolation of neural stem progenitor cells. When the dopaminergic-like neurons were transplanted into the brains of 6-OHDA-induced Parkinson's disease animal models, cells survived and ameliorated the behavioral deficits of the animal models.
45 days
See additional Protocols for: Dopaminergic Neurons , Neural Ectoderm
Generation of  dopaminergic neurons from human pluripotent stem cells under defined conditions