Generation of clinically compliant retinal epithelium cells from human embryonic stem cells
This protocol describes a method to generate retinal pigmented epithelial (RPE) cells, suitable for pre-clinical studies. Stem cell-derived RPE cells were subretinally injected into the eyes of Elovl4 mice, and were shown to improve their visual acuity .
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Generation of clinically compliant retinal epithelium cells from human embryonic stem cells