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Endocrine progenitor cells are multipotent cells that develop into the five different endocrine cell types (alpha, beta, delta, PP and epsilon cells).
These cells express distinct markers such as Neurog3 that indicate their lineage commitment, and activate downstream differentiation programs. In the pancreas the differentiation of endocrine cells is non-synchronous, and lasts from the secondary transition period (which is the major time of endocrine cell differentiation) to the postnatal period.