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EMBRYONIC DEVELOPMENT & STEM CELL COMPENDIUM

Pancreas
>
Dorsal Pancreatic Bud
>
Endocrine Progenitor Cells
Pnc.DPB.EndPCs

Endocrine progenitor cells are multipotent cells that develop into the five different endocrine cell types (alpha, beta, delta, PP and epsilon cells).


These cells express distinct markers such as Neurog3 that indicate their lineage commitment, and activate downstream differentiation programs. In the pancreas the differentiation of endocrine cells is non-synchronous, and lasts from the secondary transition period (which is the major time of endocrine cell differentiation) to the postnatal period.

E9.5 - Postnatal
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent
Version 1.1 Build 20