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Adipose
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Cranial Subcutaneous White Adipose
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Subcutaneous White Adipocytes (CSWA)


Adp.CSWA.SWA
Embryonic Development
Stem Cells & Regenerative Medicine
General
 Gene Expression(14) Stem, Progenitor & Primary Cells(0) Images(1)
 Cellular Markers(0) Protocol-derived Cells(6) Literature
 HT comparisons & samples(0) Diseases & Cell Therapies(0)
 Incoming Signals(1)
 Outgoing Signals(1)
 Developmental Ontology
Prenatal
SAT
Subcutaneous White Adipocytes
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent

Gene Expression in
Subcutaneous White Adipocytes

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Gene Expression (14)
Genes expressed, or selectively not expressed in the cell. The genes are manually curated from literature and/or imported from high throughput/large scale datasets. 

The manually curated genes can be identified by the Pubmed icon in the ‘Refs’ column.

Gene Symbol
Gene Distribution
Full Name
Expression
 
 
Localization
Method(s)
R/P
HT
ISH/IS
Refs
adiponectin, C1Q and collagen domain containing
Agpat21-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
CebpaCCAAT/enhancer binding protein (C/EBP), alpha
CebpbCCAAT/enhancer binding protein (C/EBP), beta
CebpdCCAAT/enhancer binding protein (C/EBP), delta
Fabp4 (422/aP2)fatty acid binding protein 4, adipocyte
Lepleptin
Lpllipoprotein lipase
Plin1 (perilipin)perilipin 1
peroxisome proliferator activated receptor gamma
<12>

Incoming Signals for
Subcutaneous White Adipocytes

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Incoming Signals (1)
Signals that are received by the cell, or genes induced/inhibited by an unknown signal, are presented, along with their effect, source cell, signal transduction cascades, derived cells and relevant references. Signals are ordered by their outcome effect. 

Outgoing Signals of
Subcutaneous White Adipocytes

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Outgoing Signals (1)
Secreted signals, along with their cell receivers as well as their reference
 
Name
Related Gene
LeptinLep

Cultured Cells Related to
Subcutaneous White Adipocytes

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Protocol-derived Cells (6)
Cells derived from cultured stem/progenitor cells using differentiation protocol, that were matched to the cell, based on gene expression similarity
Protocol Title
Organ / Tissue
Matched Genes
HyStem+BMP4 induction of E15 PureStem™ lineAdipose, Bone, CartilageLPL, PLIN1, PPARG, FABP4
HyStem+BMP4 induction of 7SMOO32 PureStem™ lineAdiposeCEBPD, PPARG, PLIN1, CEBPB, LPL, FABP4
Generation of adipocytes from mouse embryonic stem cellsAdiposeFabp4, Lpl
Differentiation of human bone marrow-derived mesenchymal stem cells into adipocytesAdiposeCEBPA, FABP4, LPL, PPARG
Generation of adipocytes from human pluripotent stem cells using viral transductionAdiposeFABP4, LPL, PLIN1, PPARG, ADIPOQ
Generation of adipocytes from human multipotent adipose-derived stem cellsAdiposeFABP4, PPARG

Developmental Ontology of
Subcutaneous White Adipocytes

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Develops from (1)
Developmental ancestor(s) of the cell
 

Images Related to
Subcutaneous White Adipocytes

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Literature related to
Subcutaneous White Adipocytes

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References (7)
Bibliographic references, specifying the relevance of the citation, including links to PubMed
Relevance
Title
 
Journal
Year
Author
  • Development
  • Disease
  • Gene Expression
  • Description
  • Signaling
Developmental origin of fat: tracking obesity to its source.Cell2007 Gesta S et. al.
  • Development
  • Gene Expression
Concise review: adipocyte origins: weighing the possibilities.Stem Cells2011 Majka SM et. al.
  • Development
  • Gene Expression
  • Signaling
The generation of adipocytes by the neural crest.Development2007 Billon N et. al.
  • Gene Expression
Myogenic gene expression signature establishes that brown and white adipocytes originate from distinct cell lineages.Proc Natl Acad Sci U S A2007 Timmons JA et. al.
  • Gene Expression
  • Signaling
Forming functional fat: a growing understanding of adipocyte differentiation.Nat Rev Mol Cell Biol2011 Cristancho AG, Lazar MA.
  • Gene Expression
  • Signaling
Adipogenesis at a glance.J Cell Sci2011 Lowe CE et. al.
  • Gene Expression
  • Signaling
Pref-1 regulates mesenchymal cell commitment and differentiation through Sox9.Cell Metab2009 Wang Y, Sul HS.
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