Adipose stromal cells (SCs) reside in the subcutaneous adipose tissue. SCs include cells that function as adipocyte progenitor cells (preadipocytes). Adipose SCs population, termed processed lipoaspirate (PLA) cells, can be isolated from human lipoaspirates and, like mesenchymal stem cells (MSCs), differentiate in vitro toward the osteogenic, adipogenic, myogenic, chondrogenic, hepatocytes, neuronal cells and cardiomyocyte lineages.
Locally or systemically injected adipose stromal cells (ATSCs), whether freshly isolated or expanded, stimulate angiogenesis and mediate recovery of muscle tissues following ischemic insult.
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