Forebrain white matter make up the deeper regions of the cerebral cortex which consists mostly of glia cells (oligodendrocytes and astrocytes) and myelinating axons that transmit signals from one region of the cerebral cortex to another and between the cerebral cortex and lower brain centers. The myelin sheaths are produced by oligodendrocytes, surround the axons and act as an insulator, which is essential for rapid propagation of action potentials of axons in the brain.
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