The lens placode in the embryonic ocular surface ectoderm contacts the underlying optic vesicle, triggering simultaneous of the two, to give rise to the lens pit and optic cup, respectively. The lens pit subsequently detaches from the overlying ectoderm, creating a hollow lens vesicle containing lens vesicle precursor cells. The overlying ectoderm develops into the other anterior structures including the corneal, limbus and conjunctiva epithelium and the eyelid.
In the mouse, the lens placode appears at E9.5; in humans, this occurs on day 28 of gestation.
Multiple AncestorsSingle AncestorNo DescendantsDevelops fromPart of Parent