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Transitional Lens Fiber Cells (Lns)


Eye.Lns.TLFCs
Embryonic Development
Stem Cells & Regenerative Medicine
General
 Gene Expression(10) Stem, Progenitor & Primary Cells(0) Images(1)
 Cellular Markers(0) Protocol-derived Cells(0) Literature
 HT comparisons & samples(0) Diseases & Cell Therapies(0)
 Incoming Signals(0)
 Outgoing Signals(0)
 Developmental Ontology
Transitional lens fiber cells are new fiber cells born in the equator region, that migrate inward and elongate from the anterior to posterior lens.
Prenatal - Postnatal
Lens
Transitional Lens Fiber Cells
Multiple Ancestors Single Ancestor No Descendants Develops from Part of Parent

Gene Expression in
Transitional Lens Fiber Cells

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Gene Expression (10)
Genes expressed, or selectively not expressed in the cell. The genes are manually curated from literature and/or imported from high throughput/large scale datasets. 

The manually curated genes can be identified by the Pubmed icon in the ‘Refs’ column.

Gene Symbol
Gene Distribution
Full Name
Expression
 
 
Localization
Method(s)
R/P
HT
ISH/IS
Refs
Aqp5aquaporin 5ISP
Cdkn1b (p27Kip1)cyclin-dependent kinase inhibitor 1B
Cdkn1c (p57Kip2)cyclin-dependent kinase inhibitor 1C (P57)
Cryabcrystallin, alpha BISHR
Jag1jagged 1
Maf (c-maf)avian musculoaponeurotic fibrosarcoma oncogene homolog
Pax6paired box 6
Prox1prospero homeobox 1ISP
Sox1SRY (sex determining region Y)-box 1
Sox2SRY (sex determining region Y)-box 2

Developmental Ontology of
Transitional Lens Fiber Cells

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Develops from (1)
Developmental ancestor(s) of the cell
Code
ELECs
 
Develops to (1)
Developmental descendant(s) of the cell
Code
YLFCs

Images Related to
Transitional Lens Fiber Cells

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Literature related to
Transitional Lens Fiber Cells

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References (3)
Bibliographic references, specifying the relevance of the citation, including links to PubMed
Relevance
Title
 
Journal
Year
Author
  • Gene Expression
Pax6: a multi-level regulator of ocular development.Prog Retin Eye Res2012 Shaham O et. al.
  • Gene Expression
Spatial expression of aquaporin 5 in mammalian cornea and lens, and regulation of its localization by phosphokinase A.Mol Vis2012 Kumari SS et. al.
  • Gene Expression
Pax6 is essential for lens fiber cell differentiation.Development2009 Shaham O et. al.
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